Human CLPX Knockdown Cell Lysate

• Cat.No.: CLPX-119HKCL
• Product Overview: WB-validated CLPX Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 69 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg CLPX KD HeLa cell lysate
• Protein Families: Protease
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: CLPX ClpX caseinolytic peptidase X homolog (E. coli) [ Homo sapiens (human) ]
• Official Symbol: CLPX
• Synonyms: CLPX; caseinolytic mitochondrial matrix peptidase chaperone subunit X; EPP2; ATP-dependent clpX-like chaperone, mitochondrial; ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ClpX caseinolytic peptidase X homolog; ClpX caseinolytic protease X homolog; energy-dependent regulator of proteolysis; EC 3.6.4.10
• Gene ID: 10845
• mRNA Refseq: NM_006660
• Protein Refseq: NP_006651
• MIM: 615611
• UniProt ID: O76031