Human FOXO1 Knockdown Cell Lysate

• Cat.No.: FOXO1-502HKCL
• Product Overview: WB-validated FOXO1 Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 70 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg FOXO1 KD HT-1080 cell lysate
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Insulin signaling pathway, Pathways in cancer, Prostate cancer
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: FOXO1 forkhead box O1 [ Homo sapiens (human) ]
• Official Symbol: FOXO1
• Synonyms: FOXO1; forkhead box O1; FKHR, forkhead homolog in rhabdomyosarcoma, FOXO1A; forkhead box protein O1; FKH1; forkhead box protein O1A; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; FKHR; FOXO1A
• Gene ID: 2308
• mRNA Refseq: NM_002015
• Protein Refseq: NP_002006
• MIM: 136533
• UniProt ID: Q12778