Human GLO1 Knockdown Cell Lysate

• Cat.No.: GLO1-346HKCL
• Product Overview: WB-validated GLO1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 21 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg GLO1 KD HeLa cell lysate
• Protein Pathways: Pyruvate metabolism
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: GLO1 glyoxalase I [ Homo sapiens (human) ]
• Official Symbol: GLO1
• Synonyms: GLO1; glyoxalase I; lactoylglutathione lyase; GLOD1; glyoxalase domain containing 1; glx I; aldoketomutase; methylglyoxalase; ketone-aldehyde mutase; lactoyl glutathione lyase; S-D-lactoylglutathione methylglyoxal lyase; GLYI
• Gene ID: 2739
• mRNA Refseq: NM_006708
• Protein Refseq: NP_006699
• MIM: 138750
• UniProt ID: Q04760