Human HLTF Knockdown Cell Lysate

• Cat.No.: HLTF-200HKCL
• Product Overview: WB-validated HLTF Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 114 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg HLTF KD HeLa cell lysate
• Protein Families: Druggable Genome, Transcription Factors
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: HLTF helicase-like transcription factor [ Homo sapiens (human) ]
• Official Symbol: HLTF
• Synonyms: HLTF; helicase-like transcription factor; SMARCA3, SNF2L3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3; HIP116A; HLTF1; RNF80; SNF2-like 3; RING finger protein 80; sucrose nonfermenting-like 3; sucrose nonfermenting protein 2-like 3; DNA-binding protein/plasminogen activator inhibitor 1 regulator; DNA-binding protein/plasminogen activator inhibitor-1 regulator; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3; ZBU1; HIP116; SNF2L3; SMARCA3
• Gene ID: 6596
• mRNA Refseq: NM_003071
• Protein Refseq: NP_003062
• MIM: 603257
• UniProt ID: Q14527