Human MRAS Knockdown Cell Lysate

• Cat.No.: MRAS-244HKCL
• Product Overview: WB-validated MRAS Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 24 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg MRAS KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: MRAS muscle RAS oncogene homolog [ Homo sapiens (human) ]
• Official Symbol: MRAS
• Synonyms: MRAS; muscle RAS oncogene homolog; ras-related protein M-Ras; M RAs; R RAS3; RRAS3; muscle and microspikes RAS; ras-related protein R-Ras3; M-RAs; R-RAS3; FLJ42964
• Gene ID: 22808
• mRNA Refseq: NM_001085049
• Protein Refseq: NP_001078518
• MIM: 608435
• UniProt ID: O14807