Human NDUFS3 Knockdown Cell Lysate

• Cat.No.: NDUFS3-252HKCL
• Product Overview: WB-validated NDUFS3 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 30 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg NDUFS3 KD HeLa cell lysate
• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) [ Homo sapiens (human) ]
• Official Symbol: NDUFS3
• Synonyms: NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 3 (30kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; CI 30; complex I 30kDa subunit; NADH dehydrogenase [ubiquinone] iron sulfur protein 3; mitochondrial; CI-30kD; complex I-30kD; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit; CI-30
• Gene ID: 4722
• mRNA Refseq: NM_004551
• Protein Refseq: NP_004542
• MIM: 603846
• UniProt ID: O75489