Human PARK7 Knockdown Cell Lysate

• Cat.No.: PARK7-261HKCL
• Product Overview: WB-validated PARK7 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 20 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg PARK7 KD HeLa cell lysate
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Parkinson's disease
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: PARK7 parkinson protein 7 [ Homo sapiens (human) ]
• Official Symbol: PARK7
• Synonyms: PARK7; parkinson protein 7; Parkinson disease (autosomal recessive, early onset) 7; protein DJ-1; DJ 1; DJ1; oncogene DJ1; DJ-1; FLJ27376; FLJ34360; FLJ92274
• Gene ID: 11315
• mRNA Refseq: NM_001123377
• Protein Refseq: NP_001116849
• MIM: 602533
• UniProt ID: Q99497