Human PRDX5 Knockdown Cell Lysate

• Cat.No.: PRDX5-277HKCL
• Product Overview: WB-validated PRDX5 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 22 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg PRDX5 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: PRDX5 peroxiredoxin 5 [ Homo sapiens (human) ]
• Official Symbol: PRDX5
• Synonyms: PRDX5; peroxiredoxin 5; peroxiredoxin-5, mitochondrial; ACR1; Alu co repressor 1; antioxidant enzyme B166; AOEB166; B166; liver tissue 2D page spot 71B; MGC117264; MGC142283; MGC142285; peroxisomal antioxidant enzyme; PLP; PMP20; PRDX6; PRXV; SBBI10; thioredoxin peroxidase PMP20; TPx type VI; prx-V; peroxiredoxin V; alu corepressor 1; Alu co-repressor 1; thioredoxin reductase; liver tissue 2D-page spot 71B
• Gene ID: 25824
• mRNA Refseq: NM_012094
• Protein Refseq: NP_036226
• MIM: 606583
• UniProt ID: P30044