Human RELB Knockdown Cell Lysate

• Cat.No.: RELB-510HKCL
• Product Overview: WB-validated RELB Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in several cellular components, including centrosome; chromatin; and nucleoplasm. Part of nucleus and transcription repressor complex. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 62 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg RELB KD HT-1080 cell lysate
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: MAPK signaling pathway
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: RELB v-rel reticuloendotheliosis viral oncogene homolog B [ Homo sapiens (human) ]
• Official Symbol: RELB
• Synonyms: RELB; v-rel reticuloendotheliosis viral oncogene homolog B; v rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B cells 3); transcription factor RelB; REL B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); IREL; I-REL; REL-B
• Gene ID: 5971
• mRNA Refseq: NM_006509
• Protein Refseq: NP_006500
• MIM: 604758
• UniProt ID: Q01201