Human SPINK5 Knockdown Cell Lysate

• Cat.No.: SPINK5-299HKCL
• Product Overview: WB-validated SPINK5 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 121 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg SPINK5 KD HeLa cell lysate
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: SPINK5 serine peptidase inhibitor, Kazal type 5 [ Homo sapiens (human) ]
• Official Symbol: SPINK5
• Synonyms: SPINK5; serine peptidase inhibitor, Kazal type 5; serine protease inhibitor, Kazal type 5; serine protease inhibitor Kazal-type 5; DKFZp686K19184; FLJ21544; FLJ97536; FLJ97596; FLJ99794; LEKTI; LETKI; lymphoepithelial Kazal type related inhibitor; NETS; NS; VAKTI; lymphoepithelial Kazal-type-related inhibitor; lympho-epithelial Kazal-type-related inhibitor
• Gene ID: 11005
• mRNA Refseq: NM_001127698
• Protein Refseq: NP_001121170
• MIM: 605010
• UniProt ID: Q9NQ38