Human SYNE3 Knockdown Cell Lysate

• Cat.No.: SYNE3-495HKCL
• Product Overview: WB-validated SYNE3 Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: Enables actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Involved in cytoskeleton organization; establishment of protein localization to membrane; and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 112 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg SYNE3 KD HT-1080 cell lysate
• Protein Families: Transmembrane
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: SYNE3 spectrin repeat containing nuclear envelope family member 3 [ Homo sapiens (human) ]
• Official Symbol: SYNE3
• Synonyms: SYNE3; spectrin repeat containing nuclear envelope family member 3; KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341; nesprin-3; KASH domain-containing protein 3; long intergenic non-protein coding RNA 341; nuclear envelope spectrin repeat protein 3; uncharacterized protein C14orf113
• Gene ID: 161176
• mRNA Refseq: NM_152592
• Protein Refseq: NP_689805
• MIM: 610861
• UniProt ID: Q6ZMZ3