Human TARBP2 Knockdown Cell Lysate

• Cat.No.: TARBP2-441HKCL
• Product Overview: WB-validated TARBP2 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 39 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg TARBP2 KD HeLa cell lysate
• Protein Families: Stem cell - Pluripotency
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: TARBP2 TAR (HIV-1) RNA binding protein 2 [ Homo sapiens (human) ]
• Official Symbol: TARBP2
• Synonyms: TARBP2; TAR (HIV-1) RNA binding protein 2; Tar (HIV 1) RNA binding protein 2; RISC-loading complex subunit TARBP2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; LOQS; TRBP; TRBP1; TRBP2
• Gene ID: 6895
• mRNA Refseq: NM_004178
• Protein Refseq: NP_004169
• MIM: 605053
• UniProt ID: Q15633