Human TAX1BP1 Knockdown Cell Lysate

• Cat.No.: TAX1BP1-308HKCL
• Product Overview: WB-validated TAX1BP1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 91 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg TAX1BP1 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: TAX1BP1
• Synonyms: TAX1BP1; Tax1 (human T-cell leukemia virus type I) binding protein 1; tax1-binding protein 1; CALCOCO3; TXBP151; TRAF6-binding protein; T6BP
• Gene ID: 8887
• mRNA Refseq: NM_001079864
• Protein Refseq: NP_001073333
• MIM: 605326
• UniProt ID: Q86VP1