Human TIMM50 Knockdown Cell Lysate

• Cat.No.: TIMM50-446HKCL
• Product Overview: WB-validated TIMM50 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 40 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg TIMM50 KD HeLa cell lysate
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) [ Homo sapiens (human) ]
• Official Symbol: TIMM50
• Synonyms: TIMM50; translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae); translocase of inner mitochondrial membrane 50 homolog (yeast); mitochondrial import inner membrane translocase subunit TIM50; TIM50L; Tim50-like protein; homolog of yeast Tim50; TIM50; MGC102733
• Gene ID: 92609
• mRNA Refseq: NM_001001563
• Protein Refseq: NP_001001563
• MIM: 607381
• UniProt ID: Q3ZCQ8