Human YWHAG Knockdown Cell Lysate

• Cat.No.: YWHAG-318HKCL
• Product Overview: WB-validated YWHAG Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 28 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg YWHAG KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [ Homo sapiens (human) ]
• Official Symbol: YWHAG
• Synonyms: YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3 protein gamma; 14 3 3 gamma; KCIP-1; 14-3-3 gamma; protein kinase C inhibitor protein 1; 14-3-3GAMMA
• Gene ID: 7532
• mRNA Refseq: NM_012479
• Protein Refseq: NP_036611
• MIM: 605356
• UniProt ID: P61981