- Arthrobacter sp.(1)
- Zebrafish(1)
Monoamine Oxidase B (MAO-B) Inhibitor Screening Kit (Fluorometric)
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Cat.No. : | Kit-2362 |
Product Overview : | Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity, and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A. MAO-B is a mitochondrial-bound enzyme that is ubiquitously expressed throughout the brain and other tissues. It has been investigated in numerous studies including Parkinson’s disease, Alzheimer’s, and tobacco addiction. Specific MAO-B inhibitors such as selegiline, & rasagiline have been used to treat Parkinson’s patients, but their benefits are considered rather modest. MAO-B Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-B inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of MAO substrate. |
Applications : | Screening/studying/characterizing MAO-B inhibitors |
Storage : | -20°C |
Size : | 100 assays |
◆ Recombinant Protein
MAO-12093Z | Recombinant Zebrafish MAO | +Inquiry |
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◆ Native Protein
TOD-43 | Native Tyramine Oxidase | +Inquiry |
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◆ Assay kits
Kit-2221 | Monoamine Oxidase Activity (Total MAO/MAO-A/MAO-B) Fluorometric Assay Kit | +Inquiry |
Kit-2361 | Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric) | +Inquiry |
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