Native Human Breast Milk Lactoferrin APO

• Cat.No.: LTF-8196H
• Product Overview: Human Breast Milk Lactoferrin APO was purified from Human Breast Milk.

Specification

• Species: Human
• Source: Human Breast Milk
• Tag: Non
• Description: This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Frozen Liquid
• Purity: >98% by SDS-PAGE
• Storage: Below -20 °C
• Concentration: Typically >1.0 mg/mL
• Publications:
  Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 (2021)

Gene Information

• Gene Name: LTF lactotransferrin [ Homo sapiens ]
• Official Symbol: LTF
• Synonyms: LTF; lactotransferrin; HLF2; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; LF; GIG12
• Gene ID: 4057
• mRNA Refseq: NM_001199149
• Protein Refseq: NP_001186078
• MIM: 150210
• UniProt ID: P02788
• Chromosome Location: 3p21.31
• Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem
• Function: ferric iron binding; heparin binding; metal ion binding; peptidase activity; protein binding; serine-type endopeptidase activity