| Description : |
Human Creatine Kinase is one of the most important myocardial markers (in spite of not being altogether cardiac-specific), with well-established roles in confirming acute myocardial infarction (AMI). It can also used for monitoring reperfusion during thrombolytic therapy following AMI. Testing is performed when the total Human Creatine Phosphokinase (CPK) level is elevated. Isoenzyme testing can help differentiate the source of the damaged tissue. Human CPK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Creatine Kinase MM, BB, and MB isoenzymes exist. |
| Source : |
Human Heart |
| Species : |
Human |
| Form : |
0.2 micron filtered, buffered solution, pH 7.0 with glycerol added to 50% (v/v). |
| Bio-activity : |
> 1,000 U/mL (Dimension® Clinical Chemistry System) |
| Molecular Mass : |
84000 |
| Unit Definition : |
One unit will catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37 centigrade. |
| Storage : |
Storage at -20 centigrade |
| Concentration : |
> 10 mg protein/mL (Coomassie) |
