Native Human Coagulation Factor XIIIa Protein

• Cat.No.: F13A1-321H
• Product Overview: Native Human Coagulation Factor XIIIa was purified from Plasma. Isoelectric point: 5.2 (inferred from the zymogen, factor XIII). Structure: tetramer (A2'B2) in the absence of calcium, two identical A chains (Mr=71,000) each containing 6 free sulfhydryls and and active site, two identical B subunit (Mr=88,000) identical subunits, A (Mr=75,000), B (Mr=88,000)/td>.

Specification

• Description: Plasma FXIIIa is generated by cleavage of homogenous plasma FXIII by alpha-thrombin, in the presence of EDTA. The A2'B2 subunit is purified by ion and affinity chromatography and supplied in 50% glycerol, 0.5 mM EDTA for storage at -20 centigrade.
• Source: Human Plasma
• Species: Human
• Form: 50% glycerol/500 uM EDTA (v/v)
• Molecular Mass: 312,000 Da
• Purity: >95% by SDS-PAGE
• Usage: To dilute please use a physiologic buffer such as HBS or TBS that contains ETDA to 500 micromolar. Aliquot usable sized amounts, and freeze (at -70 centigrade) the vials not being used that day. While in use keep vials on melting ice.
• Stability: Stable for 12 months.
• Storage: Store at -20 centigrade.

Gene Information

• Gene Name: F13A1 coagulation factor XIII, A1 polypeptide [ Homo sapiens ]
• Official Symbol: F13A1
• Synonyms: F13A1; coagulation factor XIII, A1 polypeptide; F13A; TGase; factor XIIIa; fibrinoligase; FSF, A subunit; coagulation factor XIIIa
• Gene ID: 2162
• mRNA Refseq: NM_000129
• Protein Refseq: NP_000120
• MIM: 134570
• UniProt ID: P00488