Native Human Immunoglobulin A1 (IgA1)

• Cat.No.: IGHA1-210H

Specification

• Species: Human
• Source: Human Plasma
• Tag: Non
• Description: In normal adult serum, the approximate percentage composition of IgA with respect to is subclasses is IgA1:90% and IgA2:10%. In secretory IgA, the subclass proportions may approach 50:50. The clinical significance of the subclasses has yet to be determined.
• Form: Frozen
• Molecular Mass: MW 160,000
• Purity: >=95% by SDS-PAGE.
• Usage: For research use only.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: -20°C
• Storage Buffer: 100 mM phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3

Gene Information

• Gene Name: IGHA1 immunoglobulin alpha 1 heavy chain constant region [ Homo sapiens ]
• Official Symbol: IGHA1
• Synonyms: IGHA1; immunoglobulin alpha 1 heavy chain constant region; IgA1; FLJ14473; FLJ41548; FLJ41552; FLJ43248; FLJ43594; FLJ44293; FLJ46028; FLJ46621; FLJ46724; FLJ46811; FLJ46824; MGC102857
• Gene ID: 3493
• Chromosome Location: 14q32.33
• Pathway: Binding and Uptake of Ligands by Scavenger Receptors, organism-specific biosystem; Inflammatory Response Pathway, organism-specific biosystem; Scavenging of heme from plasma, organism-specific biosystem
• Function: antigen binding; contributes_to immunoglobulin receptor binding