Native Human PRTN3 Protein

• Cat.No.: PRTN3-01H
• Product Overview: PRTN3 is a natural antigen having a molecular mass of 25 kDa. PRTN3 is isolated from human peripheral blood leukocytes.

Specification

• Description: Enables enzyme binding activity; serine-type endopeptidase activity; and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; membrane protein ectodomain proteolysis; and neutrophil extravasation. Located in azurophil granule lumen; cytosol; and plasma membrane raft. Colocalizes with plasma membrane.
• Source: Peripheral blood leukocytes
• Species: Human
• Molecular Mass: 25 kDa
• Purity: > 95 % in the sum of different glycosylation isoforms according to following section as determined by SDS-PAGE and capillary electrophoresis.
• Applications: WB
• Stability: Store at 4 centigrade if entire vial will be used within 2-4 weeks. Store, frozen at -20 centigrade for longer periods of time.
  Avoid multiple freeze-thaw cycles.
• Concentration: 0.5-1.0 μg/mL (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.
• Storage Buffer: 20mM Sodium Phosphate pH-6.2, 300mM NaCl, and 0.02 % Lubrol.
• Shipping: Ice packs

Gene Information

• Gene Name: PRTN3 proteinase 3 [ Homo sapiens (human) ]
• Official Symbol: PRTN3
• Synonyms: PRTN3; proteinase 3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA; myeloblastin; C-ANCA antigen; Wegener granulomatosis autoantigen; azurophil granule protein 7; leukocyte proteinase 3; neutrophil proteinase 4; serine proteinase, neutrophil; wegener autoantigen; EC 3.4.21.76
• Gene ID: 5657
• mRNA Refseq: NM_002777
• Protein Refseq: NP_002768
• MIM: 177020
• UniProt ID: P24158