Native Human Troponin Protein

• Cat.No.: Troponin-01H
• Product Overview: Native Human Troponin Protein extract from Human cardiac tissue.

Specification

• Description: Troponin I (TnI) is one of three subunits that form the troponin complex of the thin filaments of striated muscle. The troponin complex serves as a calcium-sensitive switch that regulates striated muscle contraction. Troponin I binds actin and inhibits actomyosin ATPase activity in the absence of calcium. It is expressed only in the heart and has proved to be a specific biomarker for heart disease. Cardiac troponin-I is purified by ion-exchange chromatography in conjunction with calcium dependent affinity chromatography on troponin-C agarose.
• Source: Human cardiac tissue
• Species: Human
• Molecular Mass: 24 kDa
• Purity: 95%
• Storage: At -20 centigrade (avoid repeated freeze thawing)
• Concentration: 0.25 - 2 mg/ml
• Storage Buffer: 8 M Urea, 50 mM Tris.HCl, 15 mM - mercaptoethanol, 1 mM EDTA (pH 8.0)