Native Mouse Col1a1 Protein

• Cat.No.: Col1a1-7174M
• Product Overview: Collagens were extracted from washed dissected tissue into dilute acetic acid after mild pepsin treatment. Collagen type I was purified by using differential salt precipitation. Thermal denaturation converts the collagen to gelatin.

Specification

• Description: This gene encodes the alpha-1 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-2 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice lacking the encoded protein die in utero caused by the rupture of a major blood vessel. Transgenic mice expressing significantly lower levels of this gene exhibit morphological and functional defects in mineralized and non-mineralized connective tissue and, progressive loss of hearing.
• Source: Tissue
• Species: Mouse
• Form: Liquid
• Purity: > 90 % pure by SDS PAGE. Cross linked collagen type I dimers and trimers represent approximately 10%.
• Applications: ELISA
• Stability: Shelf life: one year from despatch.
• Storage: Store the antigen undiluted at -20 centigrade only. Avoid repeated freezing and thawing.
• Concentration: 1.0 mg/mL
• Storage Buffer: 0.5 M Acetic Acid without additives.

Gene Information

• Gene Name: Col1a1 collagen, type I, alpha 1 [ Mus musculus (house mouse) ]
• Official Symbol: Col1a1
• Synonyms: Col1a1; collagen, type I, alpha 1; Co; Col; Col1; Mov-; Cola1; Mov13; Cola-1; Mov-13; Col1a-1; collagen alpha-1(I) chain; alpha-1 type 1 collagen; alpha-1 type I collagen; procollagen, type I, alpha 1
• Gene ID: 12842
• mRNA Refseq: NM_007742
• Protein Refseq: NP_031768
• UniProt ID: P11087