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p300 Inhibitor Screening Assay Kit (Fluorometric)

Cat.No. : Kit-1076
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  • Gene Information
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Applications : Screening/studying/characterizing potential inhibitors of p300
Storage : -80°C
Size : 100 assays

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Specific RNA targets or motifs recognized by EIF4A3 include splice sites and exon junctions, with functional significance in maintaining mRNA integrity. 10/16/2022

Specific transcription factors and coactivators, such as p53, CREB, and CBP, interact with p300, playing roles in gene expression and cellular responses.

Eukaryotic translation initiation factor 4A3 (EIF4A3) primarily functions in cellular processes, playing a role in RNA metabolism, including splicing and translation. 08/07/2022

p300 (EP300) plays a crucial role in cellular processes and gene regulation, serving as a transcriptional coactivator.

EIF4A3 contributes to the regulation of RNA metabolism by participating in splicing, translation initiation, and mRNA surveillance. 01/07/2021

p300 functions as a histone acetyltransferase (HAT), catalyzing the acetylation of histones and influencing chromatin modification.

There are potential therapeutic implications related to EIF4A3 in diseases involving RNA metabolism, making it a target for drug development. 08/10/2019

There are potential therapeutic implications related to p300 in diseases involving gene regulation, making it a target for drug development.

EIF4A3 is predominantly localized in the nucleus and cytoplasm of cells, contributing to its involvement in RNA-related processes. 02/20/2019

p300 is predominantly localized in the nucleus of cells, where it exerts its functions in gene regulation.

EIF4A3 influences the balance between mRNA quality control, including nonsense-mediated decay, and translation efficiency. 11/27/2018

p300 contributes to the regulation of cell cycle progression and apoptosis, influencing cell fate decisions.

Dysregulation or abnormal expression of EIF4A3 is associated with conditions such as cancer and neurodegenerative disorders. 11/20/2016

Dysregulation or abnormal expression of p300 is associated with various diseases, including cancer and neurodegenerative disorders.

Customer Reviews (3)

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Reviews
06/26/2018

    Clear and accessible protocols made it easy for all team members to contribute to our research efforts.

    05/06/2017

      We anticipated the product's future contributions to our evolving research objectives.

      03/19/2016

        We appreciated that the product adhered to relevant regulatory standards, ensuring the ethical conduct of our experiments.

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