Recombinant Active Human D2HGDH Protein, His-tagged, Animal Free
Cat.No. : | D2HGDH-02H |
Product Overview : | Recombinant Active Full length Human D2HGDH Protein (Animal free) with His tag C-Terminus was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. |
Source : | E. coli |
Species : | Human |
Tag : | His tag C-Terminus |
Form : | Lyophilized |
Bio-activity : | The specific activity of D2HGDH is ≥ 90,000 mU/mg. |
Molecular Mass : | 39 kDa |
AA Sequence : | MKVLCYGVRDVELPIFEACNKEFGY DIKCVPDYLNTKETAEMAAGFDAVI LRGNCFANKQNLDIYKKLGVKYILT RTAGTDHIDKEYAKELGFPMAFVPR YSPNAIAELAVTQAMMLLRHTAYTT SRTAKKNFKVDAFMFSKEVRNCTVG VVGLGRIGRVAAQIFHGMGATVIGE DVFEIKGIEDYCTQVSLDEVLEKSD IITIHAPYIKENGAVVTRDFLKKMK DGAILVNCARGQLVDTEAVIEAVES GKLGGYGCDVLDGEASVFGKDLEGQ KLENPLFEKLVDLYPRVLITPHLGS YTDEAVKNMVEVSYQNLKDLAETGD CPNKIKMGSSHHHHHHSSGLVPRGS HM |
Purity : | ≥ 99% SDS-PAGE |
Applications : | Functional Studies, SDS-PAGE |
Storage : | Shipped at 4 centigrade. Store at +4 centigrade short term (1-2 weeks). Store at -20 centigrade. Avoid freeze/thaw cycle. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
Reconstitution : | Reconstitute in water to a concentration of 0.1-5 mg/mL. The solution can be diluted into other aqueous buffers and stored at –20 centigrade for future use. |
Gene Name : | D2HGDH D-2-hydroxyglutarate dehydrogenase [ Homo sapiens (human) ] |
Official Symbol : | D2HGDH |
Synonyms : | D2HGDH; D-2-hydroxyglutarate dehydrogenase; D2HGD; D-2-hydroxyglutarate dehydrogenase, mitochondrial; EC 1.1.99.39 |
Gene ID : | 728294 |
mRNA Refseq : | NM_152783 |
Protein Refseq : | NP_689996 |
MIM : | 609186 |
UniProt ID : | D2RJU7 |
Products Types
◆ Recombinant Protein | ||
D2HGDH-969D | Recombinant Zebrafish D2HGDH Protein (56-533 aa), His-SUMO-tagged | +Inquiry |
D2HGDH-712H | Recombinant Human D2HGDH Protein, His (Fc)-Avi-tagged | +Inquiry |
D2HGDH-4339H | Recombinant Human D2HGDH Protein, GST-tagged | +Inquiry |
D2HGDH-2180M | Recombinant Mouse D2HGDH Protein, His (Fc)-Avi-tagged | +Inquiry |
D2HGDH-1628D | Recombinant Danio Rerio D2HGDH Protein (56-533 aa), His-tagged | +Inquiry |
◆ Lysates | ||
D2HGDH-7088HCL | Recombinant Human D2HGDH 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2108 | D-2-Hydroxyglutarate Dehydrogenase Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket