Recombinant Human D2HGDH protein, His & T7-tagged
Cat.No. : | D2HGDH-1657H |
Product Overview : | Recombinant Human D2HGDH aa. (Arg56~Asp232 (Accession # Q8N465)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 22.8kDa |
Protein length : | Arg56~Asp232 (Accession # Q8N465) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 6.7 |
Gene Name : | D2HGDH D-2-hydroxyglutarate dehydrogenase [ Homo sapiens (human) ] |
Official Symbol : | D2HGDH |
Synonyms : | D2HGDH; D-2-hydroxyglutarate dehydrogenase; D2HGD; D-2-hydroxyglutarate dehydrogenase, mitochondrial |
Gene ID : | 728294 |
mRNA Refseq : | NM_001287249.1 |
Protein Refseq : | NP_001274178.1 |
UniProt ID : | Q8N465 |
Products Types
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D2HGDH-1086H | Recombinant Human D2HGDH Protein (14-521 aa), His-SUMO-tagged | +Inquiry |
D2HGDH-02H | Recombinant Active Human D2HGDH Protein, His-tagged, Animal Free | +Inquiry |
D2HGDH-4339H | Recombinant Human D2HGDH Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
D2HGDH-7088HCL | Recombinant Human D2HGDH 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2108 | D-2-Hydroxyglutarate Dehydrogenase Fluorometric Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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