Recombinant Active Human NEK10 Protein, GST-tagged

• Cat.No.: NEK10-34H
• Product Overview: Recombinant human NEK10 (266-895) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Plays a role in the cellular response to UV irradiation. Mediates G2/M cell cycle arrest, MEK autoactivation and ERK1/2-signaling pathway activation in response to UV irradiation. In ciliated cells of airways, it is involved in the regulation of mucociliary transport.
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: Approx 98 kDa
• Protein length: 266-895
• Purity: > 85%
• Stability: One year at -70 centigrade from data of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05 μg/μL
• Storage Buffer: Recombinant protein stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Shipping: Dry ice

Gene Information

• Gene Name: NEK10 NIMA related kinase 10 [ Homo sapiens (human) ]
• Official Symbol: NEK10
• Synonyms: NEK10; NIMA related kinase 10; CILD44; serine/threonine-protein kinase Nek10; NIMA (never in mitosis gene a)- related kinase 10; never in mitosis A-related kinase 10; nimA-related protein kinase 10; EC 2.7.11.1
• Gene ID: 152110
• mRNA Refseq: NM_152534
• Protein Refseq: NP_689747
• MIM: 618726
• UniProt ID: Q6ZWH5