Recombinant Bacillus subtilis ALBG protein, His-tagged

• Cat.No.: ALBG-0866B
• Product Overview: Recombinant Bacillus subtilis ALBG full length or partial length protein was expressed.

Specification

• Source: E. coli or Yeast
• Species: Bacillus subtilis
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 80% by SDS-PAGE
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage buffer: PBS buffer

Gene Information

• Gene Name: albG antilisterial bacteriocin subtilosin biosynthesis protein AlbG [ Bacillus subtilis subsp. subtilis str. 168 ]
• Official Symbol: ALBG
• Synonyms: ALBG; antilisterial bacteriocin subtilosin biosynthesis protein AlbG
• Gene ID: 937060
• UniProt ID: P71005

Reviews

03/14/2022

I am certain that the ALBG protein will play a pivotal role in facilitating robust and insightful research, providing the assurance of reliable and consistent results.

06/02/2018

Whether I am studying protein-protein interactions, investigating cellular pathways, or examining protein folding dynamics, the ALBF protein consistently delivers exceptional performance and precise outcomes.

09/06/2016

The excellent technical support provided by the manufacturer can solve my problem.

Q&As

Can ALBG protein be used for predicting treatment response in certain diseases?

There is limited research suggesting that ALBG protein levels may have predictive value in some diseases. For example, a study found that baseline ALBG protein levels could predict treatment response in patients with hepatocellular carcinoma receiving transarterial chemoembolization. However, more studies are needed to validate these findings and determine the predictive value of ALBG protein in other diseases and treatments.

Is ALBG protein associated with any diseases?

ALBG protein itself is not directly associated with any diseases. However, its deficiency, as seen in analbuminemia, can have significant health implications. Analbuminemia is a rare genetic disorder characterized by extremely low or undetectable levels of albumin and ALBG proteins in the blood.

Can ALBG protein be used as a diagnostic marker for any diseases?

ALBG protein has been investigated as a potential diagnostic marker for certain diseases. Increased levels of ALBG protein have been associated with inflammation and infection, making it a possible marker for these conditions. Additionally, altered ALBG protein levels have been reported in liver diseases, such as cirrhosis and hepatocellular carcinoma, suggesting its potential as a diagnostic marker for these conditions. However, further research is needed to validate its clinical utility as a diagnostic marker.

What are the functions of ALBG protein in the body?

The exact functions of ALBG protein in the body are not yet fully understood. Since it is structurally related to amidase enzymes, it is speculated that ALBG protein may have catalytic activity and be involved in the metabolism of certain molecules. Some studies have also suggested that ALBG protein may play a role in modulating immune responses and inflammation. However, more research is needed to determine the precise functions and mechanisms of action of ALBG protein in the body.

Is ALBG protein being studied in any clinical trials?

I do not have specific information on whether ALBG protein is currently being studied in any clinical trials. However, it is important to note that clinical trials are continuously being conducted, and it is worth checking current clinical trial databases or consulting medical professionals for the most up-to-date information on ongoing research involving ALBG protein.

Is ALBG protein involved in any other physiological processes in the body?

While the exact role of ALBG protein in various physiological processes is not fully understood, several studies suggest its involvement in immune regulation and inflammation. It has been shown to modulate the activation and function of certain immune cells, indicating its potential role in immune responses. ALBG protein has also been found to interact with various pro-inflammatory and anti-inflammatory molecules, suggesting its involvement in inflammation modulation.

Can ALBG protein be measured in clinical laboratory tests?

Yes, ALBG protein can be measured in clinical laboratory tests. The most common method for measuring ALBG protein levels is through immunoassays, such as enzyme-linked immunosorbent assay (ELISA). ELISA kits specific for ALBG protein are commercially available, allowing for the quantification of ALBG levels in patient samples, such as blood or serum. These measurements can provide information about the concentration of ALBG protein and its potential relationship with certain diseases or conditions.

What are the potential therapeutic applications of ALBG protein?

The potential therapeutic applications of ALBG protein are still being explored, but several areas of interest include drug delivery systems and gene therapy. ALBG protein has properties that make it a potential carrier for drug delivery, as it can bind to certain molecules and target specific tissues or cells.

Are there any clinical implications or therapeutic uses of ALBG protein?

While the precise clinical implications of ALBG protein are still being investigated, some studies have suggested that it may have potential therapeutic applications. For example, ALBG protein has been investigated as a potential biomarker for certain diseases, such as liver diseases and certain cancers. Additionally, its ability to bind and transport molecules has led to research exploring its potential role in drug delivery systems and targeted therapy.

Are there any known side effects or health implications associated with ALBG protein deficiency?

ALBG protein deficiency, as seen in individuals with analbuminemia, can have significant health implications. Analbuminemia is a rare genetic disorder characterized by extremely low or undetectable levels of albumin and ALBG proteins in the blood.

Is ALBG protein expressed in all tissues of the body?

ALBG protein is primarily expressed in the liver, where it is synthesized and secreted by hepatocytes into the bloodstream. However, studies have also reported its expression in other tissues, albeit at lower levels. ALBG expression has been detected in the brain, kidney, lung, and gastrointestinal tract, suggesting additional functions or roles in these tissues. Further research is needed to elucidate the exact expression pattern and functions of ALBG protein in different tissues.

How is ALBG protein measured or detected?

ALBG protein levels can be measured using various laboratory techniques. One common method is an enzyme-linked immunosorbent assay (ELISA), in which specific antibodies are used to detect and quantify the protein in blood or other biological samples.

Are there any genetic variations or mutations associated with ALBG protein?

Yes, genetic variations and mutations in the ALBG gene have been reported. These variations can result in altered levels or activity of the ALBG protein. For example, certain single nucleotide polymorphisms (SNPs) in the ALBG gene have been associated with varying levels of ALBG protein in the blood. Additionally, some rare mutations in the ALBG gene have been linked to a condition called analbuminemia, which is characterized by extremely low levels of albumin and ALBG proteins in the blood.

Are there any specific drugs or treatments that target ALBG protein?

Currently, there are no specific drugs or treatments that specifically target ALBG protein. However, as mentioned earlier, the potential of utilizing ALBG protein for drug delivery systems is being investigated. This involves attaching drugs or therapeutic molecules to ALBG protein for targeted delivery to specific tissues or cells. Some studies have also explored the use of ALBG protein as a carrier for gene therapy, where it can deliver genetic material or therapeutic genes to target cells.

Can ALBG protein be used as a therapeutic target?

The potential therapeutic targeting of ALBG protein is still being explored. Some studies have suggested that the ability of ALBG to bind and transport molecules, such as drugs and hormones, could be utilized for drug delivery systems or targeted therapy. However, further research is needed to fully understand the implications and potential therapeutic applications of targeting ALBG protein.

How is ALBG protein regulated in the body?

The regulation of ALBG protein synthesis and secretion is not yet fully understood. However, it is known that ALBG protein is primarily synthesized and secreted by hepatocytes in the liver. The production and release of ALBG protein are likely influenced by various factors, including genetic and environmental factors that affect albumin synthesis. Further research is needed to elucidate the exact mechanisms that regulate ALBG protein expression and secretion in the body.

What conditions or diseases are associated with alterations in ALBG protein levels?

Alterations in ALBG protein levels have been observed in several conditions and diseases. For example, increased levels of ALBG protein have been reported in inflammation, infection, certain cancers, and liver diseases. On the other hand, decreased levels of ALBG protein have been associated with autoimmune diseases, kidney diseases, and malnutrition.

Are there any ongoing research studies or clinical trials involving ALBG protein?

As of now, there is limited information regarding ongoing research studies or clinical trials specifically focused on ALBG protein. However, the field of drug delivery systems utilizing ALBG protein as a carrier is an active area of research. Scientists are exploring ways to optimize ALBG protein's properties for efficient and targeted delivery of drugs or therapeutic molecules. Additionally, studies continue to explore the expression patterns and functions of ALBG protein in various tissues, which could provide valuable insights into its potential clinical applications.