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Recombinant Bovine ADSSL1, His-tagged

Cat.No. : ADSSL1-3188B
Product Overview : Adenylosuccinate synthetase isozyme 1 (ADSSL1)
  • Specification
  • Gene Information
  • Related Products
Source : E. Coli or Yeast
Species : Bovine
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 457
Purity : >90%
Notes : Small volumes of ADSSL1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : ADSSL1 adenylosuccinate synthase like 1 [ Bos taurus ]
Official Symbol : ADSSL1
Synonyms : ADSSL1; adenylosuccinate synthetase isozyme 1; adSS 1; AMPSase 1; IMP--aspartate ligase 1; M-type adenylosuccinate synthetase; adenylosuccinate synthetase, basic isozyme; adenylosuccinate synthetase, muscle isozyme
Gene ID : 784089
mRNA Refseq : NM_001099192
Protein Refseq : NP_001092662
UniProt ID : A5PJR4
Chromosome Location : chromosome: 21
Pathway : Adenine ribonucleotide biosynthesis, IMP =>ADP,ATP, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem
Function : GTP binding; adenylosuccinate synthase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How is the subcellular localization of ADSSL1 protein controlled, and are there any specific mechanisms or signals involved? 10/31/2022

The subcellular localization of ADSSL1 protein is primarily within mitochondria, facilitated by mitochondrial targeting sequences and import machinery.

Are there any known post-translational modifications or regulatory factors that modulate the activity or stability of ADSSL1 protein? 10/17/2022

Post-translational modifications, such as phosphorylation or acetylation, and regulatory factors like metabolic signals or protein-protein interactions, may modulate the activity or stability of ADSSL1 protein.

Does ADSSL1 protein interact with other proteins or participate in protein complexes, and if so, what are the functional implications? 03/19/2022

ADSSL1 protein can interact with other enzymes involved in purine metabolism, forming complexes that regulate nucleotide synthesis and energy metabolism.

Are there any genetic variations or mutations in the ADSSL1 gene that impact the expression or function of ADSSL1 protein? 12/14/2019

Genetic variations or mutations in the ADSSL1 gene can impact the expression or function of ADSSL1 protein, potentially leading to disorders associated with purine metabolism abnormalities.

What is the role of ADSSL1 protein in specific metabolic pathways or cellular processes? 11/19/2018

ADSSL1 protein plays a critical role in purine nucleotide metabolism, contributing to the deamination and recycling of adenylosuccinate to maintain nucleotide homeostasis.

Are there any specific structural features or domains of ADSSL1 protein that contribute to its enzymatic activity and substrate specificity? 07/20/2018

ADSSL1 protein contains conserved structural domains, including a catalytic domain and nucleotide-binding motifs, that contribute to its enzymatic activity and substrate specificity.

What is the enzymatic activity of ADSSL1 protein, and how is it measured in experimental assays? 02/15/2018

The enzymatic activity of ADSSL1 protein, catalyzing the conversion of adenylosuccinate to AMP, can be measured using enzymatic assays that quantify substrate utilization and product formation.

What experimental approaches, such as knockout or overexpression studies, have been employed to investigate the functional significance of ADSSL1 protein? 01/04/2018

Experimental approaches such as knockout or overexpression studies have been utilized to investigate the functional significance of ADSSL1 protein, revealing its role in cellular metabolism and energy balance.

What are the tissue-specific expression patterns of ADSSL1 protein and the factors that contribute to its regulation? 01/10/2017

ADSSL1 protein exhibits tissue-specific expression, with higher levels observed in skeletal muscle, heart, and brain. Factors involved in its regulation include transcriptional control and signaling pathways.

How does dysregulation or dysfunction of ADSSL1 protein affect cellular metabolism and contribute to disease development? 04/08/2015

Dysregulation or dysfunction of ADSSL1 protein can disrupt cellular purine metabolism, leading to imbalances in nucleotide levels and potential contributions to diseases such as neurodegenerative disorders or metabolic syndromes.

Customer Reviews (3)

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Reviews
11/01/2020

    Exploring protein-protein interactions involved in intracellular trafficking.

    06/04/2019

      Detecting protein-protein interactions in membrane receptor signaling.

      01/05/2018

        Understanding protein-protein interaction networks in DNA repair processes.

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