Recombinant Bovine B4GALT1 Protein (1-24 aa), GST-tagged

• Cat.No.: B4GALT1-350B
• Product Overview: Recombinant Bovine B4GALT1 Protein (1-24 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Protein Description: Partial.

Specification

• Description: The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the Extracellular domain matrix.
• Source: E. coli
• Species: Bovine
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 29.5 kDa
• Protein length: 1-24 aa
• AA Sequence: MKFREPLLGGSAAMPGASLQRACR
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.
• UniProt ID: P08037

Gene Information

• UniProt ID: P08037

Reviews

10/14/2021

Quick shipping, excellent quality.

10/03/2021

High quality, excellent performance.

05/16/2021

Reliable, good for research.

Q&As

How does B4GALT1 contribute to the synthesis of glycoproteins and glycolipids?

It synthesizes lactosylceramide, a building block for complex glycosphingolipids in glycoprotein and glycolipid synthesis.

What is the primary function of B4GALT1 in cellular processes?

B4GALT1 is crucial for glycosylation, attaching galactose to proteins and lipids.

In which cells or tissues is B4GALT1 predominantly expressed?

B4GALT1 is widely expressed but has higher activity in the liver, kidney, and intestine.

What therapeutic strategies are being explored targeting B4GALT1 for disease treatment?

Therapeutic strategies include targeting B4GALT1 to modulate its activity in cancer and other diseases.

How is B4GALT1 implicated in cancer progression and metastasis?

Altered B4GALT1 expression is linked to cancer, influencing tumor growth and metastasis.

Are there known genetic mutations in B4GALT1 associated with specific diseases or conditions?

Genetic mutations in B4GALT1 are associated with some rare metabolic disorders.

What role does B4GALT1 play in immune system function?

It modulates immune responses by altering glycosylation patterns on immune cells.