Recombinant Bovine MBL2 Protein (21-249 aa), His-tagged
Cat.No. : | MBL2-1452B |
Product Overview : | Recombinant Bovine MBL2 Protein (21-249 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
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Description : | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complent pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. |
Source : | Yeast |
Species : | Bovine |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 26.4 kDa |
Protein length : | 21-249 aa |
AA Sequence : | DTETENCENIRKTCPVIACGPPGIN GIPGKDGRDGAKGEKGEPGQGLRGS QGPPGKMGPQGTPGIPGIPGPIGQK GDPGENMGDYIRLATSERATLQSEL NQIKNWLIFSLGKRVGKKAFFTNGK KMPFNEVKTLCAQFQGRVATPMNAE ENRALKDLVTEEAFLGITDQETEGK FVDLTGKGVTYQNWNDGEPNNASPG EHCVTLLSDGTWNDIACSASFLTVC EFSL |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | MBL2 mannose binding lectin 2 [ Bos taurus (cattle) ] |
Official Symbol : | MBL2 |
Synonyms : | MBL; |
Gene ID : | 281297 |
mRNA Refseq : | NM_174107.2 |
Protein Refseq : | NP_776532 |
UniProt ID : | O02659 |
Products Types
◆ Recombinant Protein | ||
MBL2-1453H | Recombinant Human MBL2 Protein (21-248 aa), His-tagged | +Inquiry |
Mbl2-4928M | Recombinant Mouse Mbl2 protein(19-244aa), His-tagged | +Inquiry |
Mbl2-3980M | Recombinant Mouse Mbl2 Protein, Myc/DDK-tagged | +Inquiry |
MBL2-4449H | Recombinant Human MBL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mbl2-4922R | Recombinant Rat Mbl2 protein(19-244aa), GST-tagged | +Inquiry |
◆ Lysates | ||
MBL2-001HCL | Recombinant Human MBL2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMBL2 binds to the surface of pathogens, triggering the activation of the complement system, which leads to the destruction of the pathogens.
Yes, altered levels of MBL2 in the blood can serve as a biomarker for certain infections and immune-related disorders.
Yes, MBL2 deficiencies have been linked to an increased susceptibility to various infections and autoimmune diseases.
Yes, genetic variations in the MBL2 gene can lead to variations in MBL2 protein levels and functionality.
Yes, targeting MBL2 in drug development may offer new avenues for modulating the immune response and treating infectious and autoimmune diseases.
Customer Reviews (3)
Write a reviewThe use of MBL2 protein in such analyses provides valuable structural insights that contribute to the elucidation of ANO2's functional mechanisms and potential drug targeting sites.
MBL2 protein has shown great utility in protein electron microscopy structure analysis.
By visualizing the structural features, interactions, and conformational changes of MBL2, researchers gain valuable insights into its function and potential for therapeutic interventions.
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