Recombinant Bovine NR1H2 Protein, His-tagged

• Cat.No.: NR1H2-83B
• Product Overview: Recombinant Bovine NR1H2 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed.
• Source: E. coli
• Species: Bovine
• Tag: His
• Form: 50mM Hepes, 0.3M NaCl (pH7.0).
• Molecular Mass: 50.8 kDa
• AA Sequence: MHHHHHHSTPTTNSVDTPLPGNGPS TPSSSPGGKEDGPEPCPGGADPDVP STDGADSASVVVILDTAEEPERKRK KGPAPKMLGDELCQVCGDTASGFHY NVLSCEGCKGFFRRSVIRGGAGRYA CRGGGTCQMDAFMRRKCQQCRLRKC KEAGMREQCVLSKEQIRKKKIRKQQ QQQQQQSSPTGPGVSSSSPASGPGA SPGGSDGGGQGSGEGEGVQLTAAQE LMIQQLVAAQLQCNKRSFSDQPKVT PWPLGADPQSRDARQQRFAHFTELA IISVQEIVDFAKQVPGFLQLGREDQ IALLKASTIEIMLLETARRYNHETE CITFLKDFTYSKDDFHRAGLQVEFI NPIFEFSRAMRRLGLDDAEYALLIA INIFSADRPNVQEPSRVEALQQPYV DALLSYTRIKRPQDQLRFPRMLMKL VSLRTLSSVHSEQVFALRLQDKKLP PLLSEIWDVHE
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.35 mg/ml

Gene Information

• Gene Name: NR1H2 nuclear receptor subfamily 1 group H member 2 [ Bos taurus (cattle) ]
• Official Symbol: NR1H2
• Synonyms: NER; UNR; LXRB; LXR-b; NER-I; RIP15
• Gene ID: 509622
• mRNA Refseq: NM_001014883
• Protein Refseq: NP_001014883
• UniProt ID: Q5BIS6