| Species : |
Brevibacillus Sp |
| Source : |
E.coli |
| Tag : |
His |
| Protein Length : |
1-1090 |
| Description : |
CRISPR (clustered regularly interspaced short palindromic repeat) and CRISPR-associated (Cas) proteins constitute the adaptive immune system in bacteria. This system has been redesigned to create an exemplary genome editing tool for RNA-based therapeutics development. Cas12 and Cas13 have collateral nucleotide cleavage activities and are widely used in CRISPR-based diagnostic platforms. BrCas12b from Brevibacillus shows robust trans-cleavage activity at ideal LAMP (loop-mediated isothermal amplification) temperature. The thermal stability of BrCas12b enables one-pot target nucleic detection to minimize carryover contamination. |
| Stability : |
One year at -70 centigrade from dare of shipment. |
| Storage : |
Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated handling and multiple freeze/thaw cycles. |
| Concentration : |
0.23 μg/μL |
| Storage Buffer : |
150mM imidazole, 50mM sodium phosphate, pH 7.5, 1mM DTT, 10% glycerol. |
