Recombinant Canine CCL19 Protein

Cat.No. : CCL19-4365C
Product Overview : Recombinant Canine CCL19 Protein (77aa) was expressed in yeast.
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Source : Yeast
Species : Canine
Form : Lyophilized
Molecular Mass : 8.6 kDa
Protein length : 77aa
AA sequence : GANDAEDCCL SVTQRPIPGN IVRAFHYLLI KDGCRLPAVV FTTLKGRQLC APPDQPWVDR IIRRLQKNSA KNKGHSS (77)
Purity : >95% as visualized by SDS-PAGE analysis.
Applications : This endotoxin-free recombinant protein can be used in cell culture, ELISA Standard, and as a Western Blot Control.
Storage : Store at -20 centigrade.
Gene Name : CCL19 C-C motif chemokine ligand 19 [ Canis lupus familiaris (dog) ]
Official Symbol : CCL19
Synonyms : CCL19
Gene ID : 448793
mRNA Refseq : NM_001005256.1
Protein Refseq : NP_001005256.1
UniProt ID : Q68AY7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the limitations of research on CCL19? 10/20/2022

There are still some limitations in the current research on CCL19, such as the lack of in-depth research on its specific mechanism of action and function, and the incomplete understanding of its relationship with diseases. In addition, since CCL19 is a multifunctional protein, regulating it may also have some side effects.

Why is CCL19 related to other chemokines or proteins? 05/29/2022

It has a complex relationship with other chemokines or proteins. For example, it binds to the CCR7 receptor, which directs the migration of immune cells. In addition, CCL19 interacts with other chemokines and cytokines to jointly regulate immune responses.

What are the treatment strategies for CCL19? 05/04/2022

Therapeutic strategies for CCL19 include inhibition of its expression, modulation of its activity, or use of gene therapy. For example, some studies have shown that the use of small molecule inhibitors or antibodies against CCL19 can inhibit its activity and thus treat some CCL19-related diseases. In addition, related diseases can also be treated by regulating the expression level of CCL19.

How can we better understand the role of CCL19 in disease? 02/20/2022

In order to better understand the role of CCL19 in disease, further in-depth study of its specific mechanism of action and function is needed. In addition, it is also necessary to study the changes in its expression level and activity in different diseases, as well as its relationship with the occurrence and development of diseases. At the same time, it is also necessary to explore the clinical application prospects and effects of the therapeutic strategies that regulate them. This will contribute to the development of more effective treatments to improve outcomes and quality of life for patients with CCL19-related diseases.

What is the role of CCL19 in the immune system? 12/19/2021

CCL19 is mainly involved in the recruitment and activation of immune cells. It is able to exert immune defense by binding to receptors on the cell surface to direct immune cells to migrate to the site of inflammation or infection. In addition, CCL19 is also able to regulate the activation and differentiation of immune cells, affecting the type and intensity of immune responses.

Are there new mechanisms of action or functions in recent studies of CCL19? 10/13/2020

Recent studies have found that CCL19 is also involved in the production and maintenance of lymphatic vessels. These processes have an important impact on the migration of immune cells and the regulation of immune responses, and also provide new ideas for the treatment of some diseases related to CCL19.

Customer Reviews (3)

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03/29/2021

    The quality of the production is stable, and the batch-to-batch and intra-batch repeatability is good.

    11/10/2020

      CCL19 has a complete range of specifications and is suitable for experiments of different scales.

      03/09/2020

        The preparation is simple and we can do it ourselves.

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