Recombinant Chicken Interleukin 1, Beta

• Cat.No.: IL1B-589C
• Product Overview: Recombinant Chicken IL1Bis a 23 kDa protein and was expressed in E. coli.

Specification

• Cat. No.: IL1B-589C
• Description: IL1B is apro-inflammatory cytokine secreted by many different cell types which actsupon a wide range of target cells, resulting in a diverse range of effects.The biological properties of IL1B include the induction of B cellproliferation, stimulation of T cell proliferation in conjunction with IL-2and the production of collagenase and prostaglandin by fibroblasts. IL1B isalso responsible for triggering the acute-phase response in the liver, and isinvolved in both cytokine network and vascular endothelium activation.
• Form: Purified His-taggedrecombinant protein expressed in E.coli - liquid.
• Application: Functional Assays;In vitro Assay
• Preparation: Recombinant protein prepared from E.coli.
• Molecular Weight: approximately 23kD
• Purity: > 85% by Nichelate Chromatography
• Concentration: 250 ug/ml
• Storage: Store at -20oC only. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.

Gene Information

• Gene Name: IL1B interleukin 1, beta [ Gallusgallus ]
• Official Symbol: IL1B
• Synonyms: IL1B; interleukin 1,beta; IL1beta; IL-1BETA; interleukin-1 beta; IL-1 beta
• Gene ID: 395196
• mRNA Refseq: NM_204524
• Protein Refseq: NP_989855
• Chromosome Location: 22
• Pathway: Apoptosis;Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Herpessimplex infection; Influenza A; MAPK signaling pathway; Myometrial Relaxationand Contraction Pathways; NOD-like receptor signaling pathway; Salmonellainfection; Toll-like receptor signaling pathway
• Function: cytokineactivity; interleukin-1 receptor binding; protein domain specific binding