Recombinant Clostridium Botulinum BOTD Protein (1-442 aa), His-B2M-tagged
| Cat.No. : | BOTD-2494C |
| Product Overview : | Recombinant Clostridium Botulinum BOTD Protein (1-442 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Protein Description: Partial. |
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| Description : | Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '60-Lys-|-Leu-61' bond of synaptobrevins-1 and -2. |
| Source : | E. coli |
| Species : | Clostridium Botulinum |
| Tag : | His-B2M |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 64.5 kDa |
| Protein length : | 1-442 aa |
| AA Sequence : | MTWPVKDFNYSDPVNDNDILYLRIP QNKLITTPVKAFMITQNIWVIPERF SSDTNPSLSKPPRPTSKYQSYYDPS YLSTDEQKDTFLKGIIKLFKRINER DIGKKLINYLVVGSPFMGDSSTPED TFDFTRHTTNIAVEKFENGSWKVTN IITPSVLIFGPLPNILDYTASLTLQ GQQSNPSFEGFGTLSILKVAPEFLL TFSDVTSNQSSAVLGKSIFCMDPVI ALMHELTHSLHQLYGINIPSDKRIR PQVSEGFFSQDGPNVQFEELYTFGG LDVEIIPQIERSQLREKALGHYKDI AKRLNNINKTIPSSWISNIDKYKKI FSEKYNFDKDNTGNFVVNIDKFNSL YSDLTNVMSEVVYSSQYNVKNRTHY FSRHYLPVFANILDDNIYTIRDGFN LTNKGFNIENSGQNIERNPALQKLS SESVVDLFTKVCLRLTK |
| Purity : | > 85% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Synonyms : | botD; |
| UniProt ID : | P19321 |
| Synonyms : | botD; |
| UniProt ID : | P19321 |
Products Types
| ◆ Recombinant Protein | ||
| BOTD-1584C | Recombinant Clostridium Botulinum BOTD Protein (1-442 aa), His-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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