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Recombinant COVID-19 NSP1 protein, His-tagged

Cat.No. : NSP1-001V
Product Overview : Recombinant COVID-19 NSP1 full length or partial length protein was fused to His-tag and expressed in HEK293.
  • Specification
  • Gene Information
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Description : Inhibits host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation. By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.
Source : HEK293
Species : COVID-19
Tag : His
Form : PBS, pH7.4.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Storage : Store it at 4 ºC for short time. For long term storage, store it at -20ºC to -80ºC.
Warning : For Research Use Only.
Gene Name : orf1ab
Official Symbol : orf1ab
Synonyms : pp1ab
Gene ID : 1489680
Protein Refseq : NP_828860.2
UniProt ID : P0C6X7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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