Recombinant COVID-19 NSP3 protein, His-tagged
| Cat.No. : |
NSP3-81V |
| Product Overview : |
Recombinant COVID-19 NSP3 full length or partial length protein was fused to His-tag and expressed in HEK293. |
- Specification
- Gene Information
- Related Products
| Description : |
Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling. |
| Source : |
HEK293 |
| Species : |
COVID-19 |
| Tag : |
His |
| Form : |
PBS, pH7.4. |
| Endotoxin : |
< 1.0 EU per μg of the protein as determined by the LAL method. |
| Purity : |
>80% |
| Storage : |
Store it at 4 ºC for short time. For long term storage, store it at -20ºC to -80ºC. |
| Warning : |
For Research Use Only. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
