Recombinant COVID-19 NSP8 protein, His-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
|Product Overview :||Recombinant COVID-19 NSP8 protein (Ala1-Gln198) was fused to his-tag at the N-terminus and expressed in E.coli.|
|Description :||NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of COVID-19, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.|
|Predicted N Terminal :||Met|
|Form :||Delivered as bulk protein in a 0.2 μm filtered solution of 20 mM Tris, 250 mM NaCl, pH8.5 with glycerol as protectant.|
|Molecular Mass :||The protein has a calculated MW of 23.9 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Protein length :||Ala1-Gln198|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.|
|Storage :||Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
|Shipping :||This product is supplied as sterile liquid solution and shipped frozen with dry ice, please inquire the shipping cost.|
|SDS-PAGE of NSP8-198V :||
COVID-19 NSP8, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
|Gene Name :||ORF1ab|
|Official Symbol :||ORF1ab|
|Synonyms :||ORF1a polyprotein|
|Gene ID :||43740578|
|Protein Refseq :||YP_009725304.1|
|UniProt ID :||P0DTD1|