Recombinant COVID-19 Spike RBD + SD1 + SD2 protein, His-tagged

• Cat.No.: Spike-210V
• Product Overview: Recombinant COVID-19 spike protein receptor binding domain together with subdomain 1 and subdomain 2 (Glu309-Ala684), fused to His-tag at the C-terminus, was expressed in HEK293F.

Specification

• Species: Sars-CoV-2
• Source: HEK293
• Tag: His
• Description: It's been reported that COVID-19 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
• Form: Liquid in sterile PBS, pH 7.4.
• Molecular Mass: Predicted molecular weight: 42.9 kDa
• Endotoxin: <0.1 EU per ug of protein as determined by LAL method.
• Purity: 95% or above
• Storage: The protein is stable in a liquid state at -70 centigrade for 12 months. Avoid repeated freeze-thaw cycles.
• Concentration: See product label
• Shipping: Recombinant proteins are provided as frozen liquid and will be shipped out with dry ice.
• Warning: For research use only.

Gene Information

• Gene Name: S
• Official Symbol: S
• Synonyms: spike glycoprotein
• Gene ID: 43740568
• Protein Refseq: YP_009724390.1
• UniProt ID: P0DTC2