Recombinant Cynomolgus CD200, His tagged

• Cat.No.: CD200-123C
• Product Overview: Recombinant Cynomolgus CD200 (F7GN60) (Met1-Gly232), fused with a polyhistidine tag at the C-terminus, was produced in Human Cells.

Specification

• Source: Human Cells
• Species: Cynomolgus
• Tag: His&Fc
• Predicted N Terminal: Gln 31
• Form: Lyophilized from sterile PBS, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
• Molecular Mass: The recombinant cynomolgus CD200 comprises 213 amino acids and has a calculated molecular mass of 24 KDa. The apparent molecular mass of it is approximately 39-43 KDa respectively in SDS-PAGE.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Protein length: Met1-Gly232

Gene Information

• Gene Name: CD200?CD200 molecule [?Macaca fascicularis?(crab-eating macaque) ]
• Official Symbol: CD200
• Gene ID: 102146004
• mRNA Refseq: XM_005548171
• Protein Refseq: XP_005548228
• Chromosome Location: 2

Reviews

08/01/2022

Swift protein sequencing, helps identify unknown proteins.

05/04/2022

Great protein crystallization services, key for structural biology.

05/02/2019

Invaluable protein-protein interaction assays, integral for research.

Q&As

How does CD200 contribute to the regulation of bone marrow and hematopoietic stem cell niches?

CD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.

How does CD200 influence tumor immune evasion and the tumor microenvironment in cancer?

CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.

What role does CD200 play in the suppression of inflammatory responses in autoimmune diseases?

CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.

What are the effects of CD200 dysregulation on tissue graft rejection and transplant tolerance?

Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.

How do alterations in CD200 expression impact the aging process and age-related immune changes?

Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.

What is the impact of CD200 expression on neuroinflammatory processes and neurodegenerative diseases?

CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.

How does CD200 interact with its receptor CD200R, and what are the implications for immune regulation?

CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.