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Recombinant Human CD200, Fc-His tagged

Cat.No. : CD200-629H
Product Overview : Recombinant Human CD200 extracellular domain (Met 1-Gly 232) (NP_005935.4), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
Availability February 12, 2025
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Source : Human Cells
Species : Human
Tag : His&Fc
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The recombinant human CD200/Fc is a disulfide-linked homodimer. The reduced monomer consists of 450 amino acids and has a predicted molecular mass of 50.5 kDa. As a result of glycosylation, the apparent molecular mass of rh CD200/Fc monomer is approximately 65-70 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Protein length : Met1-Gly232
Gene Name : CD200 CD200 molecule [ Homo sapiens ]
Official Symbol : CD200
Gene ID : 4345
mRNA Refseq : NM_001004196
Protein Refseq : NP_001004196
MIM : 155970
UniProt ID : P41217

Not For Human Consumption!

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Customer Reviews (3)

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08/01/2022

    Swift protein sequencing, helps identify unknown proteins.

    05/04/2022

      Great protein crystallization services, key for structural biology.

      05/02/2019

        Invaluable protein-protein interaction assays, integral for research.

        Q&As (7)

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        How does CD200 contribute to the regulation of bone marrow and hematopoietic stem cell niches? 10/04/2022

        CD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.

        How does CD200 influence tumor immune evasion and the tumor microenvironment in cancer? 07/10/2021

        CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.

        What role does CD200 play in the suppression of inflammatory responses in autoimmune diseases? 04/06/2021

        CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.

        What are the effects of CD200 dysregulation on tissue graft rejection and transplant tolerance? 02/09/2019

        Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.

        How do alterations in CD200 expression impact the aging process and age-related immune changes? 09/17/2018

        Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.

        What is the impact of CD200 expression on neuroinflammatory processes and neurodegenerative diseases? 03/20/2018

        CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.

        How does CD200 interact with its receptor CD200R, and what are the implications for immune regulation? 03/18/2018

        CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.

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