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Recombinant Cynomolgus IL3RA protein, His-tagged

Cat.No. : IL3RA-179C
Product Overview : Recombinant Cynomolgus IL3RA protein(G8F3K3-1)(Arg18-Arg302), fused with C-terminal His tag, was expressed in HEK293.
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Source : HEK293
Species : Cynomolgus
Tag : C-His
Protein length : Arg18-Arg302
Form : Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Bio-activity : Human IL-3, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-3 R alpha, His Tag with an affinity constant of 0.46 μM as determined in SPR assay (Biacore T200).
Molecular Mass : The protein has a predicted MW of 33.9 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
Endotoxin : Less than 1EU per μg by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE
Storage : Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Reconstitution : Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
07/24/2022

    In special environment, good stability.

    05/25/2022

      Good crystallization property and good effect.

      06/29/2021

        Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on.

        Q&As (6)

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        Can Il3ra be personalized? 08/01/2022

        The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.

        Does Il3ra have clinical application prospects? What are the prospects? 05/19/2022

        Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.

        What is the action mechanism of Il3ra? 04/24/2022

        Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.

        How is the clinical trial of Il3ra progressing? 09/16/2020

        Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.

        What is the specific effect of Il3ra on the immune system? 08/06/2019

        The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.

        Does Il3ra have side effects? 05/24/2019

        Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.

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