Recombinant Cynomolgus IL3RA protein, His-tagged
Cat.No. : | IL3RA-179C |
Product Overview : | Recombinant Cynomolgus IL3RA protein(G8F3K3-1)(Arg18-Arg302), fused with C-terminal His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Cynomolgus |
Tag : | C-His |
Protein length : | Arg18-Arg302 |
Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
Bio-activity : | Human IL-3, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-3 R alpha, His Tag with an affinity constant of 0.46 μM as determined in SPR assay (Biacore T200). |
Molecular Mass : | The protein has a predicted MW of 33.9 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result. |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE |
Storage : | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Reconstitution : | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewIn special environment, good stability.
Good crystallization property and good effect.
Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on.
Q&As (6)
Ask a questionThe feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
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