Recombinant Cynomolgus IL6 protein, His-tagged
| Cat.No. : | IL6-1500C |
| Product Overview : | Recombinant Cynomolgus IL6 protein(P79341)(Ala28-Met212), fused with C-terminal His tag, was expressed in HEK293. |
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| Source : | HEK293 |
| Species : | Cynomolgus |
| Tag : | C-His |
| Protein length : | Ala28-Met212 |
| Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Bio-activity : | Immobilized Cynomolgus IL-6, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 13.8ng/ml determined by ELISA. |
| Molecular Mass : | The protein has a predicted MW of 22.06 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |
| Endotoxin : | Less than 1EU per μg by the LAL method. |
| Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC. |
| Storage : | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Reconstitution : | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Products Types
| ◆ Recombinant Protein | ||
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| IL6-351I | Active Recombinant Human IL6 Protein (185 aa) | +Inquiry |
| ◆ Lysates | ||
| IL6-5224HCL | Recombinant Human IL6 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewAccurate localization and function within the cell.
The binding affinity and affinity constant with the target are high.
Can form a stable micellar structure.
Q&As (6)
Ask a questionThe dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.
The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.
Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.
Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.
This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.
The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.
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