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Recombinant Cynomolgus INSIG1 Protein, His-tagged

Cat.No. : INSIG1-624C
Product Overview : Recombinant Cynomolgus INSIG1 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Cynomolgus
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : INSIG1 insulin induced gene 1 [ Macaca fascicularis (crab-eating macaque) ]
Official Symbol : INSIG1
Synonyms : INSIG1;
Gene ID : 102147014
mRNA Refseq : NM_001287692
Protein Refseq : NP_001274621
MIM :
UniProt ID : I7GKV6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does INSIG1 contribute to cellular lipid droplet formation? 04/14/2022

INSIG1 contributes to cellular lipid droplet formation by influencing lipid homeostasis and storage in response to sterol levels.

Is INSIG1 involved in the regulation of triglyceride metabolism? 01/08/2022

While INSIG1 primarily regulates cholesterol synthesis, its indirect influence on triglyceride metabolism is observed through modulation of SREBP-regulated pathways.

How does INSIG1 impact the degradation of HMG-CoA reductase? 02/09/2020

INSIG1 promotes the degradation of HMG-CoA reductase, a key enzyme in cholesterol synthesis, through ubiquitination and proteasomal degradation.

Are there any known inhibitors or activators of INSIG1? 12/07/2018

There are no widely recognized small-molecule inhibitors or activators of INSIG1 identified to date.

What is the significance of INSIG1 in the feedback regulation of cholesterol synthesis? 03/28/2018

INSIG1 is crucial in the feedback regulation of cholesterol synthesis, preventing excess cholesterol production by inhibiting the activation of SREBP proteins.

Does INSIG1 expression respond to changes in cellular sterol levels? 08/08/2017

Yes, the expression of INSIG1 is responsive to changes in cellular sterol levels, serving as a key component of the sterol-sensing mechanism.

What is the role of INSIG1 in the unfolded protein response (UPR)? 02/26/2017

INSIG1 is involved in the unfolded protein response (UPR), a cellular stress response pathway associated with endoplasmic reticulum (ER) stress.

Customer Reviews (3)

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Reviews
07/19/2021

    We found the product's safety and biocompatibility reassuring, especially when handling sensitive samples.

    07/23/2018

      Precise immunoprecipitation results consistently reflected the product's quality.

      07/20/2017

        The product's innovative characteristics enabled us to delve into previously uncharted cellular mechanisms.

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