Recombinant Cynomolgus INSIG1 Protein, His-tagged
Cat.No. : | INSIG1-624C |
Product Overview : | Recombinant Cynomolgus INSIG1 full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Cynomolgus |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | INSIG1 insulin induced gene 1 [ Macaca fascicularis (crab-eating macaque) ] |
Official Symbol : | INSIG1 |
Synonyms : | INSIG1; |
Gene ID : | 102147014 |
mRNA Refseq : | NM_001287692 |
Protein Refseq : | NP_001274621 |
MIM : | |
UniProt ID : | I7GKV6 |
Products Types
◆ Recombinant Protein | ||
INSIG1-2734R | Recombinant Rat INSIG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG1-370C | Recombinant Cynomolgus Monkey INSIG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG1-4562M | Recombinant Mouse INSIG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG1-10242Z | Recombinant Zebrafish INSIG1 | +Inquiry |
INSIG1-129H | Recombinant Human INSIG1 protein, His-GST-tagged | +Inquiry |
◆ Lysates | ||
INSIG1-5193HCL | Recombinant Human INSIG1 293 Cell Lysate | +Inquiry |
INSIG1-5194HCL | Recombinant Human INSIG1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
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Q&As (7)
Ask a questionINSIG1 contributes to cellular lipid droplet formation by influencing lipid homeostasis and storage in response to sterol levels.
While INSIG1 primarily regulates cholesterol synthesis, its indirect influence on triglyceride metabolism is observed through modulation of SREBP-regulated pathways.
INSIG1 promotes the degradation of HMG-CoA reductase, a key enzyme in cholesterol synthesis, through ubiquitination and proteasomal degradation.
There are no widely recognized small-molecule inhibitors or activators of INSIG1 identified to date.
INSIG1 is crucial in the feedback regulation of cholesterol synthesis, preventing excess cholesterol production by inhibiting the activation of SREBP proteins.
Yes, the expression of INSIG1 is responsive to changes in cellular sterol levels, serving as a key component of the sterol-sensing mechanism.
INSIG1 is involved in the unfolded protein response (UPR), a cellular stress response pathway associated with endoplasmic reticulum (ER) stress.
Customer Reviews (3)
Write a reviewWe found the product's safety and biocompatibility reassuring, especially when handling sensitive samples.
Precise immunoprecipitation results consistently reflected the product's quality.
The product's innovative characteristics enabled us to delve into previously uncharted cellular mechanisms.
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