Recombinant Cynomolgus Monkey MOG Protein, His (Fc)-Avi-tagged

• Cat.No.: MOG-443C
• Product Overview: Recombinant Cynomolgus Monkey MOG with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Cynomolgus Monkey
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: MOG myelin oligodendrocyte glycoprotein [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: MOG
• Synonyms: MOG; MOG alpha-2; MOG alpha-3; MOG alpha-4; MOG alpha-6; MOG beta-1; MOG beta-2; MOG beta-3
• Gene ID: 102118842
• mRNA Refseq: NM_001284856
• Protein Refseq: NP_001271785
• UniProt ID: Q9BGS7

Reviews

11/20/2022

Excellent in protein studies.

03/14/2022

Reliable, efficient, and effective.

11/23/2021

Worked well, great quality.

Q&As

In which cells or tissues is MOG predominantly expressed?

MOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.

What role does MOG play in autoimmune demyelinating diseases?

MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.

What diagnostic or therapeutic strategies involve MOG in the context of demyelinating diseases?

MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.

Are there known genetic mutations or alterations in MOG associated with specific neurological conditions?

There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.

How does MOG contribute to the integrity and function of the myelin sheath?

MOG contributes to myelin integrity, aiding in proper nerve signal transmission.

How is MOG implicated in the pathogenesis of Multiple Sclerosis (MS)?

MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.

What is the primary function of MOG in the nervous system?

MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.