MOG

  • Official Full Name

    myelin oligodendrocyte glycoprotein

  • Overview

    The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface;of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination.;This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication.;Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms

    MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5; MOGIG2; NRCLP7; MGC26137;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Bos taurus (Bovine)
  • Callithrix jacchus (White-tufted-ear marmoset)
  • Cattle
  • Cynomolgus Monkey
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Mouse
  • Mouse/Rat
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rat
  • Rattus norvegicus (Rat)
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • NS0
  • Rabbit
  • Synthetic
  • Wheat Germ
  • C
  • 6×His
  • GFP
  • His
  • Fc
  • GST
  • HIS
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MOG-060H Active Recombinant Human MOG Protein E.coli N/A
Human MOG-641H Recombinant Human MOG, Fc-tagged Human Cell Fc
Human MOG-3828H Recombinant Human MOG protein(Gly30-Tyr149), His-tagged E. coli C-His Gly30-Tyr149
Human MOG-061H Recombinant Human MOG Protein, HIS-tagged HEK293 HIS
Human MOG-640H Recombinant Human MOG, Fc-tagged, Biotinylated Human Cell Fc
Human MOG-633H Recombinant Human MOG Protein, His-tagged E.coli His Gly30~Tyr149
Human MOG-1126HCL Recombinant Human MOG cell lysate N/A
Human CAB11583RH Rabbit Monoclonal Antibody to Human Myelin Oligodendrocyte Glycoprotein Rabbit N/A
Human MOG-5466H Recombinant Human MOG Protein, GST-tagged Wheat Germ GST
Human MOG-5453H Recombinant Human MOG Protein, MYC/DDK-tagged HEK293T Myc/DDK
Human MOG-4583H Recombinant Human MOG Protein (Gly30-Gly154), C-His tagged E.coli C-His Gly30-Gly154
Human MOG-02H Recombinant Human MOG Protein, His/Avi-tagged, Biotinylated HEK293 His/Avi
Human MOG-3593H Recombinant Human MOG Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MOG-301349H Recombinant Human MOG protein, GST-tagged E.coli GST Gly30-Gly154
Human MOG-4585H Recombinant Human MOG Protein (Gly30-Tyr149), His tagged E.coli His Gly30-Tyr149
Human MOG-063H Recombinant Human MOG Protein, C-6×His-tagged E.coli C-6×His 247
Human MOG-4405H Recombinant Human MOG protein, His-tagged E.coli His 30-154aa
Human MOG-0509H Recombinant Human MOG protein, His-tagged HEK293 His Gly30-Gly154
Human MOG-6302HF Recombinant Full Length Human MOG Protein, GST-tagged In Vitro Cell Free System GST 295 amino acids
Human MOG-4584H Recombinant Human MOG Protein (Gly30-Gly154), C-His tagged Mammalian cells C-His Gly30-Gly154
Human MOG-4586H Recombinant Human MOG Protein (Met1-Phe247), C-GFP tagged Mammalian cells C-GFP Met1-Phe247
Mouse MOG-01 Myelin oligodendrocyte glycoprotein Synthetic N/A
Mouse Mog-634M Recombinant Mouse Mog Protein, His-tagged E.coli His Gly29~Gly153
Mouse Mog-01M Recombinant Mouse Mog Protein, His-tagged E.coli His
Mouse Mog-6988M Recombinant Mouse Mog protein(Gly29-Thr156), His-tagged E. coli C-His Gly29-Thr156
Mouse Mog-4111M Recombinant Mouse Mog Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Mog-6755M Recombinant Mouse Mog Protein (Gln29-Gly125), N-His tagged E.coli N-His Gln29-Gly125
Mouse Mog-02M Active Recombinant Mouse Mog Protein, His-tagged NS0 His
Rat Mog-75R Recombinant Rat Mog protein, His-tagged E.coli His Gly28~Gly152
Bos taurus (Bovine) RFL6599BF Recombinant Full Length Bovine Myelin-Oligodendrocyte Glycoprotein(Mog) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-246)
Callithrix jacchus (White-tufted-ear marmoset) RFL25775CF Recombinant Full Length Callithrix Jacchus Myelin-Oligodendrocyte Glycoprotein(Mog) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (28-245)
Cattle MOG-632C Recombinant Cattle MOG Protein, His-tagged E.coli His Gly29~Gly153
Cynomolgus Monkey MOG-697C Recombinant Cynomolgus MOG Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey MOG-443C Recombinant Cynomolgus Monkey MOG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey MOG-443C-B Recombinant Cynomolgus Monkey MOG Protein Pre-coupled Magnetic Beads HEK293
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL24581MF Recombinant Full Length Macaca Fascicularis Myelin-Oligodendrocyte Glycoprotein(Mog) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-247)
Mouse/Rat MOG-20 Native Mouse/Rat MOG (35-55) Protein
Mus musculus (Mouse) RFL35167MF Recombinant Full Length Mouse Myelin-Oligodendrocyte Glycoprotein(Mog) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-246)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL34853PF Recombinant Full Length Pongo Abelii Myelin-Oligodendrocyte Glycoprotein(Mog) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-246)
Rattus norvegicus (Rat) RFL9094RF Recombinant Full Length Rat Myelin-Oligodendrocyte Glycoprotein(Mog) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (28-245)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MOG Related Articles
  • MOG Related Research Area

MOG involved in several pathways and played different roles in them. We selected most pathways MOG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MOG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MOG has several biochemical functions, for example, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MOG itself. We selected most functions MOG had, and list some proteins which have the same functions with MOG. You can find most of the proteins on our site.

Function Related Protein
virus receptor activityLDLR;PVRL4;HLA-DRB1;SLC52A2;CD86;PVRL1;SLC20A2;TNFRSF4;PVR

MOG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOG here. Most of them are supplied by our site. Hope this information will be useful for your research of MOG.

OTUD4

Probstel, AK; Rudolf, G; et al. Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype. JOURNAL OF NEUROINFLAMMATION 12:-(2015).
Aktas, O; et al. Collateral benefit: the comeback of MOG antibodies as a biomarker in neurological practice. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 86:243-243(2015).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
In which cells or tissues is MOG predominantly expressed? 02/14/2022

MOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.

What role does MOG play in autoimmune demyelinating diseases? 09/04/2021

MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.

What diagnostic or therapeutic strategies involve MOG in the context of demyelinating diseases? 03/03/2021

MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.

Are there known genetic mutations or alterations in MOG associated with specific neurological conditions? 06/20/2020

There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.

How does MOG contribute to the integrity and function of the myelin sheath? 06/15/2020

MOG contributes to myelin integrity, aiding in proper nerve signal transmission.

How is MOG implicated in the pathogenesis of Multiple Sclerosis (MS)? 03/30/2020

MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.

What is the primary function of MOG in the nervous system? 10/13/2018

MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.

Customer Reviews (3)

Write a review
Reviews
11/20/2022

    Excellent in protein studies.

    03/14/2022

      Reliable, efficient, and effective.

      11/23/2021

        Worked well, great quality.

        Ask a Question for All MOG Products

        Required fields are marked with *

        My Review for All MOG Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends