Recombinant Cynomolgus PVRIG protein, Fc-tagged
Cat.No. : | PVRIG-230C |
Product Overview : | Recombinant Cynomolgus PVRIG (Thr41-Asp171) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
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Description : | Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. |
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Thr41 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 40.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Thr41-Asp171 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PVRIG |
Official Symbol : | PVRIG |
Synonyms : | PVRIG; poliovirus receptor related immunoglobulin domain containing; transmembrane protein PVRIG; C7orf15; MGC2463; poliovirus receptor-related immunoglobulin domain-containing protein; MGC104322; MGC138295; MGC138297 |
Gene ID : | 102127364 |
mRNA Refseq : | XM_005549224.2 |
Protein Refseq : | XP_005549281.1 |
UniProt ID : | A0A2K5WVV8 |
Products Types
◆ Recombinant Protein | ||
PVRIG-685H | Recombinant Human PVRIG Protein (Thr53-Leu150), HIgG1 Fc-tagged | +Inquiry |
PVRIG-1387H | Acitve Recombinant Human PVRIG protein(Thr41-Leu172), mFc-tagged | +Inquiry |
PVRIG-3951H | Recombinant Human PVRIG Protein, His (Fc)-Avi-tagged | +Inquiry |
PVRIG-522H | Active Recombinant Human PVRIG protein(Thr41-Leu172), hFc-tagged | +Inquiry |
PVRIG-0603M | Recombinant Mouse PVRIG protein, His-tagged | +Inquiry |
◆ Lysates | ||
PVRIG-1447HCL | Recombinant Human PVRIG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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