Recombinant DENV1 NS1 Protein

• Cat.No.: NS1-03D
• Product Overview: Dengue virus serotype 1 NS1 protein is a recombinant protein, cloned and expressed in insect cells with greater than 95% purity. Protein is purified using a proprietary chromatographic technique.

Specification

• Description: Dengue virus is a globally distributed flavivirus with 4 distinct serotypes (DENV1, 2, 3 and 4) and is primarily transmitted by the Aedes aegypti mosquito, which is found throughout the tropical and subtropical regions of over 100 countries. DENV poses a significant worldwide public health threat with approximately 2.5 to 3 billion people residing in DENV endemic areas, among whom 100 to 200 million individuals will be infected and approximately 30,000 patients will succumb to the disease, annually. NS1 is produced during all four DENV infections and is released as a hexamer circulating in great quantities in acute-phase blood of infected humans. In diagnostics, DENV NS1 is used as an antigen test for rapid detection on the first day of fever, before antibodies appear some 5 or more days later. It has emerged as an alternative biomarker to both serologic and molecular based techniques for diagnosis of acute DENV infection.
• Source: Insect cell
• Species: DENV1
• Form: Liquid
• Purity: > 95%
• Applications: Immunoassay development or other applications.
• Storage: Short Term Storage: -20 centigrade
  Long Term Storage: -80 centigrade
  Multiple freeze/thaw cycles are to be avoided.
• Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide as preservative
• Shipping: Dry Ice