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Recombinant Dog CTSK Protein, His/GST-tagged

Cat.No. : CTSK-328D
Product Overview : Recombinant Dog CTSK(Thr71~Cys319) fused with His/GST tag at N-terminal was expressed in E. coli.
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Description : CTSK played an important role in many functions.
Source : E. coli
Species : Dog
Tag : His/GST
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 59.5kDa
Identity : Reconstitute in PBS or others
Protein length : Thr71~Cys319
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : CTSK cathepsin K [ Canis lupus familiaris ]
Official Symbol : CTSK
Synonyms : CTSK; cathepsin K; cathepsin K (pycnodysostosis);
Gene ID : 608843
mRNA Refseq : NM_001033996
Protein Refseq : NP_001029168
UniProt ID : Q3ZKN1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CTSK be a target for the development of novel therapeutics for periodontal diseases? 10/10/2022

Yes, CTSK inhibitors are being investigated for their potential in preventing bone loss associated with periodontal diseases.

How does CTSK contribute to the progression of atherosclerosis, and can it be a therapeutic target for cardiovascular diseases? 01/22/2020

CTSK has been linked to vascular calcification in atherosclerosis, and inhibiting its activity may have potential as a therapeutic strategy for cardiovascular diseases.

How might CTSK inhibitors impact the treatment landscape for bone metastasis in cancer patients? 03/26/2018

CTSK inhibitors could potentially be used to limit bone destruction in cancer patients with bone metastasis, improving their quality of life.

Are there any other medical conditions where CTSK inhibitors could be beneficial? 07/29/2017

CTSK inhibitors are being explored for potential therapeutic applications in conditions like rheumatoid arthritis and certain cancers due to their involvement in tissue remodeling.

Are there diagnostic applications for CTSK in identifying bone-related disorders? 11/22/2016

While CTSK is not currently used as a diagnostic marker, its levels and activity could potentially be explored for diagnostic purposes in the future.

Customer Reviews (3)

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Reviews
09/13/2019

    This guidance can help researchers design and execute their experiments more effectively, ensuring reliable and accurate results.

    01/27/2019

      They have a deep understanding of the CTSK protein and can provide valuable insights into its characteristics, properties, and optimal experimental conditions.

      12/14/2016

        the manufacturer offers outstanding technical support, serving as a valuable resource to resolve any issues that may arise during my research.

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